Archive for March, 2008

Finansteride, Minoxidil Or Both

Saturday, March 29th, 2008

hey doctor!

As I read through forums and articles, people mention that propecia works better in conjunction with something else, such as rogaine for exmaple. At the moment, the vertex area of my scalp seems “emptier” than the crown and minoxidil works well with the vertex. Do you recommend me go back on minoxidil for the vertex, or should I just focus on propecia?


Answer:

I generally prescribe finasteride to most of my patients who have significant miniaturization whether they are getting hair transplants or not. There are several studies on using Rogaine (minoxidil) and Propecia (finasteride) as single therapy and in combination with each other or with other medications.

Comparing minoxidil and finasteride for treatment of male pattern baldness clearly shows that treatment with only finasteride is more effective than treatment with only minoxidil. Combination of finasteride with minoxidil and with some other medications shows improved outcome, but the rate of improvement is not significant enough that I can convince myself to prescribe combination therapy to all my patients for the rest of their lives, considering difficulty of using topical minoxidil (topical spreading of medication twice a day on the balding area of scalp).

If you want to do everything possible to prevent or slow down further hair loss and maybe grow some, you can consider combination therapy, but remember when you start minoxidil you are committed to continue it for the rest of your life or until there are better alternatives.

Cicatricial Alopecia

Saturday, March 29th, 2008

Cicatricial alopecia refers to a group of rare skin diseases in which hair follicle get destroyed and replaced by scar tissue. It is one of the rare causes of hair loss. Hair loss could be gradual or sudden. Hair loss could be without any symptoms or it could present with sever itching, burning and pain. There is usually no visible scar, because the inflammation is below the level of skin. Cicatricial alopecia could occur in otherwise healthy men and women of all ages.

Cicatricial alopecias could be primary or secondary. This discussion is confined to the primary cicatricial alopecias in which the hair follicle is the target of the destructive inflammatory process. In secondary cicatricial alopecias, a non-follicle-directed process or external injury, such as severe infections, burns, radiation, or tumors could cause destruction of the hair follicle.

The causes of the cicatricial alopecias are not completely known. However, all cicatricial alopecias involve inflammation directed at the hair follicle, the upper part of the follicle where the stem cells and sebaceous gland are located are generally involved. Permanent hair loss occurs when the stem cells and the sebaceous glands are destroyed. This type of hair loss is usually irreversible.

Cicatricial alopecias can affect both men and women. The majority of patients with cicatricial alopecia have no family history of a similar condition. Central centrifugal cicatricial alopecia is a type of cicatricial alopecia that is more prevalent among black woman. Frontal fibrosing alopecia on the other hand is seen most commonly in post-menopausal women.

could be seen in association with chronic skin conditions such as lupus erythematosus and in people with personal or family history of autoimmune disorder. A scalp biopsy is necessary for diagnosis of cicatricial alopecia. Presence of inflammatory cells and scarring could be diagnostic and essential for determining the type of treatment.

Treatment of the lymphocytic group of cicatricial alopecias involves use of anti-inflammatory medications such as steroids, cyclosporine, hydroxychloroquine. When hair follicle destroyed, hair will not grow back. However in some cases using minoxidil solution can help to stimulate growth of some of the remaining hair. Hair transplant could only be used in the patients who have normal healthy hair in donor area. If hair multiplication becomes a reality in the future that might potentially be an option for patients who lost their scalp hair extensively as result of this condition.

Current Number of Worldwide Hair Restoration Procedures

Friday, March 28th, 2008

ISHRS Logo

Here is the statement from the International Society of Hair Restoration Surgery on the Current Number of Worldwide Hair Restoration Procedures

The International Society of Hair Restoration Surgery (ISHRS) is the world’s leading medical authority on hair – from hair loss to hair restoration – with a membership of more than 650 physicians from around the world dedicated to the advancement of the art and science of hair restoration.

In 2007, the ISHRS Practice Census found that approximately 225,800 hair restoration procedures were performed worldwide in 2006 – up 34 percent from 2004. This large increase in hair restoration procedures coincides with a significant jump in the total number of hair restoration patients around the world – from 361,077 patients in 2004 to 645,281 patients in 2006. It was also determined that patients are seeking treatment for hair loss at a younger age, with men under the age of 50 representing the largest group of patients.

While we know that other specialty medical associations may come to different conclusions on the number of hair transplants performed annually, the ISHRS believes its members’ estimates accurately reflect the growing demand for hair restoration procedures based on the fact that hair transplant surgery comprises a significant portion of our members’ medical practices.

The ISHRS 2007 Practice Census statistics are available on the Media Center of the ISHRS website at http://www.ishrs.org, and the Society encourages anyone considering a hair restoration procedure to visit its website for the latest information on the causes and available solutions for hair loss.

Dr. Parsa Mohebi on Radio and TV

Thursday, March 27th, 2008

Dr. Parsa Mohebi - Hair Transplant Surgeon and media

Dr. Parsa Mohebi has been having a series of professional talks on radio and TV on hair loss and available treatment options including medical and surgical with hair transplant procedures. We will be posting the videos and sound tracks of the Radio and TV talk programs in the website of US Hair Restoration soon.

Los Angeles Hair Transplant - LA Hair Transplant Surgeons

Wednesday, March 26th, 2008

Los Angeles hair transplant surgeons and hair transplant centers; how do they compare with hair restorations surgeons of the other cities or countries? Los Angeles is the mecca of cosmetic surgery. Is this also true in the field of hair transplant?

Los Angeles Hair Transplant - LA Hair Transplant Surgeons

Answer:
As one of the Los Angeles hair transplant surgeons, I believe there is a wide variety in quality of hair transplant surgery in the city of Los Angeles. That is also true about other branches of plastic and cosmetic surgeries in LA. Hair transplant surgery has evolved tremendously in the last two decades, but unfortunately not every hair transplant surgeon has been following the most recent findings and methods in the industry, which is the cause of differences we can see between Los Angeles hair transplant surgeons and the end result of their hair restoration procedures.

You have to chose the surgeon who is familiar with all methods of hair transplant. Some surgeons who did not get adequate training on the newer methods such as Follicular Unit Extraction (FUE) or mega session hair transplant surgeries may not be able to offer all available options to the patients.

I have to repeat, don’t choose your doctor based on the location of his hair transplant clinic. Do your homework, educate yourself with the advances in hair restoration surgery and hair transplant. LA (Los Angeles) or elsewhere does not matter. If you know what you should be looking for when looking for a hair transplant surgeon, you will know when you meet him or her.

Psychology of Hair Transplant

Wednesday, March 19th, 2008

I just received the last issue of the Hair Transplant Forum International, the Journal of International Society of Hair Restoration Surgery (ISHRS). Our article, Psychology of Hair Transplant‚ is published as the cover article on this issue of the journal. I also have a copy of the article in our hair loss library in our website. Here is the abstract:

Psychology of Hair Transplant

Hair Trnsplant Forum Inernational

Parsa Mohebi, M.D., William Rassman, M.D.

Balding and its psychological impacts has been the subject of many studies in the past. The relationship between hair loss and stress is clear to all clinicians who practice in this field. Negative psychosocial impacts of hair loss in male patterned baldness and in women with generalized thinning have also been seen. Many of us (hair transplant surgeons) have seen the negative effects of hair loss on self esteem and self-image.

We know that hair loss impacts some men sex life and their stability with regard to career choices in men of different ages. Despite the solid evidences and published literature on psychological impact of hair loss, the corrective effect of medical and surgical hair restoration has never been studied. After observing the drastic changes in patient behavior and the high level of patient satisfaction in those who had hair transplant procedure, we were motivated to look into the psychological impact of hair restoration on different aspects of a patient’s life.

Psychology of hair transplant graph

We came up with a series of criteria that could have been modified by having a hair restoration procedure; we used some indexes that were previously studied comparing bald and non bald men on different psychological variables. We initially performed a pilot study and asked patients about different aspects of their lives during their post op visits. We gave our patients open ended questionnaires and probed their psychological state after their hair restoration procedure was complete. Eventually we focused in on eight major criteria that have been reported and documented as variables associated with hair loss in the literature. We collected a subset of them in our pilot study. Included were questions on the general level of happiness, energy level, feeling of youthfulness, anxiety levels, self confidence, outlook on their future and impact on their sex life.

We have chosen the patients who had their first hair transplant surgery between one to three years from the time of our study, so they had seen the final result of their hair restoration procedure. We limited the study to male patients with male pattern baldness and the ones who had surgeries less than three years ago so they still had a fresh memory of the changes they experienced. Each patient had exclusively follicular unit transplants that reflected our standard of care for that period. We sent a questionnaire with a brief description on the nature of this scientific study. We did not collect any patient identifiers and the response was totally voluntary. We sent the two hundred questionnaires with stamped return envelope.

The response rate to our questionnaire was 37 (18%). Each patient was used as his own control since we asked about the changes that they experienced after surgery in comparison to those variables before the surgery. We used T-test to compare patient’s responses. Table 1 shows the mean and standard error in eight different criteria that were asked. Patients had significant improvements in all eight criteria regardless of their stage of baldness and their ages.

In another attempt to compare psychological changes that patients experienced in different stages of baldness, we divided patients into two groups: (1) those who had Norwood IV patterns or less and (2) the ones with Norwood V patterns and above. We observed the most significant difference in two categories, (a) sex life and (b) career experience. Patients with less balding had a greater impact on their sex life and career when compared to patients who had more advanced stages of hair loss. These changes were not age related.

Hair restoration surgery can affect many aspects of a patient’s life. Hair transplant can potentially reverse psycho-social problems associated with hair loss. The positive impact of hair restoration surgery is more visible among patients who suffer from those undesirable effects the most. In early stages of hair loss, patients may have more awareness of their condition and they might be more affected than men in the later stages of hair loss.

Patients who experienced hair loss at an early age while involved in an active social life were more prone to the negative side effects of balding. That could explain why younger people with hair loss appeared more benefited by hair restoration procedures. Also it could be assumed that hair loss can have a negative impact on a patient’s outlook which seems to reverse after receiving a hair restoration procedure which improved their outlook.

Low response rate from a blind mailing has always been a drawback in questionnaire studies. We received 37 out of 200 of the questionnaires that we sent out (response rate was 18.5%). Giving incentives to responders may be a good way of increasing the participation rate of any questionnaire studies. We presented the result of this study at the annual scientific meeting of ISHRS and have been contacted by many of our colleagues who expressed interest in collaborating in a larger scale study. We are currently trying to rise funding for repeating this study to optimize our response rate and the statistical value of the study.

If you have any questions on the content of this article you can contact US Hair Restoration office at Los Angeles through email at info@ushairrestoration or phone.

US Hair Restoration Video Clip

Thursday, March 13th, 2008

Fortune Cookie: Be Advanturesome Try A New Look

Tuesday, March 11th, 2008

We had a long hair transplant surgery today, but I could not go home before posting this title.

One of our patients at US Hair Restoration who were undergoing a hair transplant procedure ordered Chinese food for lunch and this is what he found in the fortune cookie that came with his meal.

Fortune cookie - hair transplant

Body Hair Transplant

Friday, March 7th, 2008

Question:
Hi Dr.Mohebi,

I am wondering if the chest hair be transfer to the head?

Yours,

Name

Chest Hair

Answer:
Good question and the answer is yes. Some people with limited scalp hair can be good candidates for body hair transplants. This is how it works:

Body hair can be harvested and used for hair transplants in people who have both good course body hair and are severely depleted of scalp donor hair (hair on the sides and back of the head). Body hair should not regularly be used as an alternative to scalp hair for hair transplants. This is because body hair has a short growth cycle in comparison to scalp hair, which makes body hair less desirable than scalp hair for a hair transplant.

Each scalp hair grows between 1 to 6 years and then goes to its resting phase for 4 to 6 weeks in which the hair follicle falls out before the start of another growth cycle. Body hair on the other hand has a different growth cycle, which consists of much shorter growth phase and a longer resting phase. In other words, many body hair follicles that you transplant stay in resting phase most of their lives and only a fraction of them grow and are visible at any given period of time. So you are transplanting hair follicles knowing that not many of them could be seen at any given period of time.

Having said that body hair transplants are OK for people who have no alternative ie. bad donor hair density or quality.

Side Effects of Finasteride

Thursday, March 6th, 2008

Question:

Dear Dr. Mohebi,

Dr., I had a question: say I would use proscar now and took it for a while, after how long based on studies is it possible to see adverse side effects, if any? The reason why I ask is because when I went and read the messages on the forums, I saw positive and negative feedbacks. One person used proscar for 7 years and saw nothing but great results. I would like to give it a shot and see if I am lucky, hopefully. Thank you! Have a great weekend,


Best,

Patient’s name

Fiansteride


Answer:
The side effects of finasteride (Propecia/Proscar) could be seen anytime from right after starting it to months after starting finasteride. If you read the articles on adverse effects of finasteride you can clearly see that there is a small difference between the rates of side effects from the people who took placebos to the ones taking finasteride.

Let’s face it; you are prescribing a drug to a patient telling him that it works through altering your male hormones. What do you think the chances are that the patient will have problems with his sex drive?

The good news is that the side effects of finasteride are few and the most problematic one (decreased sex drive) is only seen in one out of a hundred patients. The other good news is that even if you are in that one percent category and you decide to continue using finasteride anyway, after one year of using finasteride the rate of side effects decreases to about the rate that was shown in people who only took a placebo.